ALVESCO
ICS MDI
Ciclesonide · Covis Pharma
Active Medication & Mechanism
- Ciclesonide ICS80 mcg or 160 mcg per actuation
Pro-drug that is enzymatically hydrolyzed in the lungs to its active metabolite desisobutyryl-ciclesonide (des-CIC), which has high glucocorticoid receptor affinity and anti-inflammatory activity.
FDA-Approved Dosing — Strength × Indication
Strength Regimen AsthmaCOPD
80 mcg
1 inhalation twice daily → 160 mcg
FDA Approved
Adults (previously on bronchodilators alone) Starting dose for patients previously using bronchodilators alone. Maximum 160 mcg twice daily. US label dosing is twice daily only.
Adults (previously on inhaled corticosteroids) Starting dose for patients previously maintained on other inhaled corticosteroids. Maximum 320 mcg twice daily. US label dosing is twice daily only.
Not Approved
Alvesco is not indicated for COPD.
160 mcg
2 inhalations twice daily → 640 mcg
FDA Approved
Adults (previously on oral corticosteroids) Higher dose for patients previously on oral corticosteroids. Maximum recommended dose is 320 mcg twice daily (640 mcg/day).
Not Approved
Alvesco is not indicated for COPD.
All regimens shown apply to adults (≥18 years) unless otherwise noted · verify against current labelling
80 mcg 1 inhalation twice daily → 160 mcg
Asthma FDA Approved
Adults (previously on bronchodilators alone) Starting dose for patients previously using bronchodilators alone. Maximum 160 mcg twice daily. US label dosing is twice daily only.
Adults (previously on inhaled corticosteroids) Starting dose for patients previously maintained on other inhaled corticosteroids. Maximum 320 mcg twice daily. US label dosing is twice daily only.
COPD Not Approved
Alvesco is not indicated for COPD.
160 mcg 2 inhalations twice daily → 640 mcg
Asthma FDA Approved
Adults (previously on oral corticosteroids) Higher dose for patients previously on oral corticosteroids. Maximum recommended dose is 320 mcg twice daily (640 mcg/day).
COPD Not Approved
Alvesco is not indicated for COPD.
All regimens shown apply to adults (≥18 years) unless otherwise noted · verify against current labelling
Not a rescue inhaler. Not a rescue inhaler. Not indicated for acute episodes. Use a SABA.