ARNUITY ELLIPTA

Fluticasone Furoate

ARNUITY ELLIPTA

ICS DPI

Fluticasone furoate · GlaxoSmithKline

Clinical Reference

Active Medication & Mechanism

Fluticasone furoate ICS
50 mcg, 100 mcg, or 200 mcg per blister

Synthetic trifluorinated corticosteroid with potent anti-inflammatory activity and enhanced glucocorticoid receptor affinity. Once-daily dosing due to prolonged retention in lung tissue.

FDA-Approved Dosing by Indication

// approval varies by strength + age

Asthma

3/4 approved regimens

Strength	Population	Dose & Frequency	Total Daily	Status
50 mcg	Patients ≥5 years	1 inhalation once daily Lowest available strength; for patients ≥5 years previously on non-corticosteroid therapy or low-dose ICS.	50 mcg	FDA Approved
100 mcg	Patients ≥12 years	1 inhalation once daily For patients previously requiring medium-dose inhaled corticosteroids.	100 mcg	FDA Approved
200 mcg	Patients ≥12 years	1 inhalation once daily For patients previously requiring high-dose inhaled corticosteroids.	200 mcg	FDA Approved
Any strength	Acute bronchospasm	—	—	Not Approved Not a bronchodilator. Not for relief of acute bronchospasm. Use a SABA.

50 mcg FDA Approved

Pop · Patients ≥5 years

1 inhalation once daily

Lowest available strength; for patients ≥5 years previously on non-corticosteroid therapy or low-dose ICS.

Total · 50 mcg
100 mcg FDA Approved

Pop · Patients ≥12 years

1 inhalation once daily

For patients previously requiring medium-dose inhaled corticosteroids.

Total · 100 mcg
200 mcg FDA Approved

Pop · Patients ≥12 years

1 inhalation once daily

For patients previously requiring high-dose inhaled corticosteroids.

Total · 200 mcg
Any strength Not Approved

Pop · Acute bronchospasm

—

Total · — Not a bronchodilator. Not for relief of acute bronchospasm. Use a SABA.

COPD

0/1 approved regimens

Strength	Population	Dose & Frequency	Total Daily	Status
Any strength	Adults	—	—	Not Approved Arnuity Ellipta is not indicated for COPD.

Any strength Not Approved

Pop · Adults

—

Total · — Arnuity Ellipta is not indicated for COPD.

Acute Use

0/1 approved regimens

Strength	Population	Dose & Frequency	Total Daily	Status
Any strength	Acute bronchospasm / rescue	—	—	Not Approved Not for acute use. Use a SABA.

Any strength Not Approved

Pop · Acute bronchospasm / rescue

—

Total · — Not for acute use. Use a SABA.