SEREVENT DISKUS
LABA DPI
Salmeterol xinafoate · GlaxoSmithKline
Active Medication & Mechanism
- Salmeterol xinafoate LABA50 mcg salmeterol per blister
Long-acting beta2-adrenergic agonist. Provides sustained bronchodilation (≥12 hours) via stimulation of beta2-receptors on airway smooth muscle. Onset is approximately 30–48 minutes.
FDA-Approved Dosing — Strength × Indication
Strength Regimen AsthmaCOPDExercise-Induced Bronchospasm
50 mcg
Varies by indication — see columns
FDA Approved
Adults (≥18 years, only with concomitant ICS) 1 inhalation twice daily (~12 hours apart) → 100 mcg For asthma, should only be used as additional therapy in patients NOT adequately controlled on ICS or whose disease warrants ICS + LABA. MUST be used WITH an ICS — salmeterol monotherapy in asthma increases the risk of asthma-related death.
FDA Approved
1 inhalation twice daily (~12 hours apart) → 100 mcg Maintenance treatment of bronchospasm associated with COPD, including emphysema and chronic bronchitis.
FDA Approved
1 inhalation at least 30 minutes before exercise → Should not exceed 1 inhalation twice daily Prevention of exercise-induced bronchospasm. Do not use additional doses for 12 hours. Patients already taking Serevent twice daily should NOT use additional doses for EIB.
All regimens shown apply to adults (≥18 years) unless otherwise noted · verify against current labelling
50 mcg
Asthma FDA Approved
Adults (≥18 years, only with concomitant ICS) 1 inhalation twice daily (~12 hours apart) → 100 mcg For asthma, should only be used as additional therapy in patients NOT adequately controlled on ICS or whose disease warrants ICS + LABA. MUST be used WITH an ICS — salmeterol monotherapy in asthma increases the risk of asthma-related death.
COPD FDA Approved
1 inhalation twice daily (~12 hours apart) → 100 mcg Maintenance treatment of bronchospasm associated with COPD, including emphysema and chronic bronchitis.
Exercise-Induced Bronchospasm FDA Approved
1 inhalation at least 30 minutes before exercise → Should not exceed 1 inhalation twice daily Prevention of exercise-induced bronchospasm. Do not use additional doses for 12 hours. Patients already taking Serevent twice daily should NOT use additional doses for EIB.
All regimens shown apply to adults (≥18 years) unless otherwise noted · verify against current labelling
Not a rescue inhaler. Not for acute bronchospasm. Use a SABA.
Related Inhalers
Other LABA inhalers