SYMBICORT
ICSLABA MDI
Budesonide / Formoterol fumarate dihydrate · AstraZeneca
Active Medication & Mechanism
- Budesonide ICS80 mcg or 160 mcg per actuation
Corticosteroid with potent glucocorticoid activity and weak mineralocorticoid activity. Reduces airway inflammation by inhibiting inflammatory cells and mediators.
- Formoterol fumarate dihydrate LABA4.5 mcg per actuation
Long-acting beta2-adrenergic agonist with rapid onset of action. Relaxes bronchial smooth muscle via beta2-receptor stimulation.
FDA-Approved Dosing — Strength × Indication
Strength Regimen AsthmaCOPD
80/4.5 mcg
2 inhalations twice daily (morning and evening) → 320/18 mcg
FDA Approved
For patients not adequately controlled on long-term asthma control medication or whose disease warrants ICS/LABA.
Not Approved
The 80/4.5 mcg strength is NOT indicated for COPD. Only 160/4.5 is approved for COPD.
160/4.5 mcg
2 inhalations twice daily → 640/18 mcg
FDA Approved
For patients not controlled on medium-dose ICS. Maximum recommended dose.
FDA Approved
Maintenance treatment of airflow obstruction in COPD, including chronic bronchitis and emphysema. Reduces exacerbations.
All regimens shown apply to adults (≥18 years) unless otherwise noted · verify against current labelling
80/4.5 mcg 2 inhalations twice daily (morning and evening) → 320/18 mcg
Asthma FDA Approved
For patients not adequately controlled on long-term asthma control medication or whose disease warrants ICS/LABA.
COPD Not Approved
The 80/4.5 mcg strength is NOT indicated for COPD. Only 160/4.5 is approved for COPD.
160/4.5 mcg 2 inhalations twice daily → 640/18 mcg
Asthma FDA Approved
For patients not controlled on medium-dose ICS. Maximum recommended dose.
COPD FDA Approved
Maintenance treatment of airflow obstruction in COPD, including chronic bronchitis and emphysema. Reduces exacerbations.
All regimens shown apply to adults (≥18 years) unless otherwise noted · verify against current labelling
Not a rescue inhaler. Not for acute bronchospasm. Use a SABA.
Related Inhalers
Same active ingredients (Budesonide/Formoterol)