ASMANEX TWISTHALER

Mometasone

ASMANEX TWISTHALER

ICS DPI

Mometasone furoate · Organon

Clinical Reference

Active Medication & Mechanism

Mometasone furoate ICS
110 mcg or 220 mcg per actuation (delivers 100 mcg or 200 mcg from mouthpiece)

Synthetic corticosteroid with potent anti-inflammatory properties. Reduces airway inflammation.

FDA-Approved Dosing by Indication

// approval varies by strength + age

Asthma

3/4 approved regimens

Strength	Population	Dose & Frequency	Total Daily	Status
110 mcg	Patients ≥4 years (previously on bronchodilators alone or ICS)	1 inhalation once daily in the evening For patients 4–11 years, maximum dose is 110 mcg once daily in the evening.	110 mcg	FDA Approved
220 mcg	Patients ≥12 years (previously on bronchodilators alone or ICS)	1 inhalation once daily in the evening or 1 inhalation twice daily Recommended starting dose for patients ≥12 years previously on bronchodilators alone or inhaled corticosteroids.	220–440 mcg	FDA Approved
220 mcg	Patients ≥12 years (previously on oral corticosteroids)	2 inhalations twice daily Maximum recommended dose. For patients previously on oral corticosteroids.	880 mcg	FDA Approved
Any strength	Acute bronchospasm	—	—	Not Approved Not a bronchodilator. Not for relief of acute bronchospasm. Use a SABA.

110 mcg FDA Approved

Pop · Patients ≥4 years (previously on bronchodilators alone or ICS)

1 inhalation once daily in the evening

For patients 4–11 years, maximum dose is 110 mcg once daily in the evening.

Total · 110 mcg
220 mcg FDA Approved

Pop · Patients ≥12 years (previously on bronchodilators alone or ICS)

1 inhalation once daily in the evening or 1 inhalation twice daily

Recommended starting dose for patients ≥12 years previously on bronchodilators alone or inhaled corticosteroids.

Total · 220–440 mcg
220 mcg FDA Approved

Pop · Patients ≥12 years (previously on oral corticosteroids)

2 inhalations twice daily

Maximum recommended dose. For patients previously on oral corticosteroids.

Total · 880 mcg
Any strength Not Approved

Pop · Acute bronchospasm

—

Total · — Not a bronchodilator. Not for relief of acute bronchospasm. Use a SABA.

Acute Use

0/1 approved regimens

Strength	Population	Dose & Frequency	Total Daily	Status
Any strength	Acute bronchospasm / rescue	—	—	Not Approved Not for acute use. Use a SABA.

Any strength Not Approved

Pop · Acute bronchospasm / rescue

—

Total · — Not for acute use. Use a SABA.