FLOVENT DISKUS
ICS DPI
Fluticasone propionate · GlaxoSmithKline
Active Medication & Mechanism
- Fluticasone propionate ICS50 mcg, 100 mcg, or 250 mcg per blister
Synthetic corticosteroid with potent anti-inflammatory activity. Inhibits multiple cell types (mast cells, eosinophils, macrophages) and mediators involved in airway inflammation.
FDA-Approved Dosing by Indication
// approval varies by strength + age Asthma
3/4 approved regimens| Strength | Population | Dose & Frequency | Total Daily | Status |
|---|---|---|---|---|
| 50 mcg | Patients ≥4 years | 1 inhalation twice daily (~12 hours apart) Starting dose for patients previously on bronchodilators alone. | 100 mcg | FDA Approved |
| 100 mcg | Patients ≥12 years | 1 inhalation twice daily For patients previously on ICS or bronchodilators alone who require a moderate step-up. | 200 mcg | FDA Approved |
| 250 mcg | Patients ≥12 years | 1 inhalation twice daily For patients previously on other ICS or oral corticosteroids. Maximum dose is 500 mcg twice daily (1000 mcg/day). | 500 mcg | FDA Approved |
| Any strength | Acute bronchospasm | — | — | Not Approved Not a bronchodilator. Not for relief of acute bronchospasm. Use a SABA. |
Acute Use
0/1 approved regimens| Strength | Population | Dose & Frequency | Total Daily | Status |
|---|---|---|---|---|
| Any strength | Acute bronchospasm / rescue | — | — | Not Approved Not for acute use. Use a SABA. |